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課程名稱 |
幹細胞學導論
Introduction of Stem Cell |
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開課學期 |
112-1 |
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授課對象 |
生物資源暨農學院 動物科學技術學系 |
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授課教師 |
吳信志 |
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課號 |
AniSci3021 |
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課程識別碼 |
606 36700 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三9,10(16:30~18:20) |
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上課地點 |
畜二 |
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備註 |
總人數上限：30人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
本課程除介紹幹細胞之基礎生物學、分類及特性外，將就目前多分化潛能幹細胞及體幹細胞之研究進展各舉數個實例說明，更進一步探討幹細胞自我更新及分化之相關訊息傳遞；另將介紹人類疾病幹細胞治療動物模式之建立。
Overview the stem cells, such as somatic stem cells and pluripotent stem cells, as well as introduce to basic biology and mechanisms of stem cell self-renewal and differentiation, establishment of animal models for human diseases, stem cell therapy . |
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課程目標 |
了解幹細胞基礎生物學、人類疾病幹細胞治療及再生醫學臨床應用概況。
Transfer the knowledge related to embryonic, fetal and somatic stem cells, as well as their application in regenerative medicine for human disease. |
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課程要求 |
For graduate and undergraduate students |
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預期每週課後學習時數 |
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Office Hours |
每週二 10:00~17:00 |
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指定閱讀 |
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參考書目 |
1. Lanza, R. . 2009.Stem cell biology. 2nd edition, Elsevier Academic Press. ISBN: 978-0-12-374729-7.
2. Lanza, R. and A. Atala . 2013. Handbook of Stem Cells. Elsevier Academic Press. ISBN: 978-0-12-401719-1 (volume I), .
3. Lanza, R. and A. Atala . 2013. Handbook of Stem Cells. Elsevier Academic Press. ISBN: 978-0-12-401718-4 (volume II). |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
Midterm exam. |
40% |
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2. |
Final exam. |
40% |
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3. |
Participation |
20% |
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週次 |
日期 |
單元主題 |
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第1週 |
9/6 |
Overview the stem cells
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第2週 |
9/13 |
Basic concepts of the stem cell
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第3週 |
9/20 |
Embryonic stem cells and trophoblast stem cells
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第4週 |
9/27 |
Fetal stem cells
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第5週 |
10/4 |
Mesenchymal stem cells
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第6週 |
10/11 |
Stem cell in the eye
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第7週 |
10/18 |
Dental stem cells
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第8週 |
10/25 |
Midterm exam
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第9週 |
11/01 |
Mechanisms of stem cell self-renewal
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第10週 |
11/08 |
Telomere and telomerase regulation
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第11週 |
11/15 |
Transdifferentiation potential of adult cells and somatic stem cells
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第12週 |
11/22 |
In vitro and in vivo differentiation potential of skin stem cells
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第13週 |
11/29 |
Embryonic stem cell and nuclear transfer cloning
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第14週 |
12/06 |
Nuclear cloning and epigenetic reprogrammin |
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第15週 |
12/13 |
Establishment of animal models for human disease
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第16週 |
12/20 |
Final term exam
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